Archive for January, 2011
HOSPITAL NEUROLOGY
A meta-analysis of the three largest randomized trials comparing carotid artery stenting with carotid endarterectomy in patients with symptomatic carotid disease found that the proportion with stroke or death at 120 days after randomization was significantly higher for the stenting group. The estimated risk of stroke or death for patients age 70 and older was approximately two-fold higher for the stenting group compared with the endarterectomy group.
MRI and diffusion-weighted imaging (DWI) utilizing higher magnetic field strengths of 3 Tesla (T) units are increasingly available in clinical settings. A retrospective study found that diagnostic accuracy for early strokes, read by radiologists blinded to the machine used, was better for images taken with standard 1.5 T MRI scanners than for 3 T images. Artifacts with higher magnetic field strengths may obscure early ischemic changes.
New guidelines published by the American Academy of Neurology refine the criteria for diagnosing brain death and emphasize that there are no published reports of neurologic recovery after a diagnosis of brain death using these or the 1995 criteria.
Clinical Trial Establishes Catheter-based Aortic Valve Replacement as New Standard of Care for Patients Who Cannot Undergo Surgery
One-year data from the PARTNER clinical trial, published yesterday in the New England Journal of Medicine,demonstrate that transcatheter aortic-valve implantation, compared with standard therapy, resulted in significantly lower rates of death among patients who cannot undergo surgery for aortic stenosis. The results will be presented today as a Late Breaking Trial at the 22nd annual Transcatheter Cardiovascular Therapeutics (TCT) scientific symposium.
Transcatheter aortic-valve implantation (TAVI) is a new procedure in which a bioprosthetic valve is inserted through a catheter and implanted within the diseased native aortic valve. The Placement of AoRtic TraNscathetER valves
(PARTNER) trial is a multicenter, randomized clinical trial comparing TAVI with standard therapy in high-risk patients with severe aortic stenosis. The co-principal investigators are Martin B. Leon, M.D., and Craig R. Smith, M.D., at NewYork-Presbyterian Hospital/Columbia University Medical Center. The data published today reflect a prespecified cohort of patients who were considered to be unsuitable candidates for surgery.
Implantable Artificial Kidney Research Aims to Replace Dialysis
Researchers at the University of California, San Francisco (UCSF) Department of Bioengineering and Therapeutic Sciences, in collaboration with a nationwide research team, have developed a prototype for a bioartificial kidney that is designed to eliminate the need for dialysis treatments within the decade. This breakthrough medical device creates a two-stage process to replicate normal kidney functioning. Thousands of nanoscale filters will remove toxins from the blood, while a BioCartridge of renal tubule cells acts to replicate the metabolic and water-balance roles of the human kidney.
The two-stage treatment design embedded in the artificial kidney model has already been validated in the treatment of kidney failure patients –but the current application of this technique is only available from a room-sized external model developed by a team member in Michigan. To make the artificial kidney implantable, the researchers will use specialized nanotechnology and materials to reduce its size dramatically, to about the size of a coffee cup.
Though much work remains, the research team hopes to have an implantable size device ready for clinical trials in 5-7 years. This kidney treatment breakthrough promises to have an enormous impact on patient lives as well as medical costs. There are over half a million people in the U.S. suffering from end-stage renal disease, or chronic kidney failure. These patients require regular dialysis treatments and can only be fully treated with a kidney transplant. Medicare system alone spends $25 billion on treatments for kidney failure every year– more than 6 percent of the total Medicare budget.
Bad Habits – 5 Reasons Why You Are Not a Good Candidate For Dental Implants
You are probably already aware of the importance of a healthy, active lifestyle. You are probably also aware that poor diet habits and bad lifestyle choices can result in health complications in later life. What you may not know is that these same lifestyle choices can have a profound effect on the success of your new dental implants. Shocked? Read more to find out 10 lifestyle choices which can greatly increase the risk of Dental Implant Failure.
1. High Sugar Diet
A high sugar diet especially when young can increase your chances of developing periodontal gum disease. All gum disease must be treated by a specialist prior to the fitting of any tooth implants. The more severe the disease the lower your chances of having a quick, problem free dental implant procedure.
2. Heavy smoking
Heavy smoking is generally bad for your teeth and gums but if you do opt to have oral implant surgery you should be aware that smoking slows down and hinders the healing process once the implant is fitted. In addition the expected life time of dental implants for smokers is somewhat reduced.
A Review of Aloe Vera Benefits
Known for its benefits to keep your hair healthy, Aloe Vera also has many other benefits you have to know well. Originally comes from Africa, this herb contains a lots of substances such as minerals, vitamins and enzymes which transfer a huge numbers of advantages for your body. According from the research of expert, for those who have a diabetic’s symptoms Aloe Vera could deal with this disease preventively.
As the matters of fact, for those who are diagnosed have high blood sugar level, you are recommending lowering the level of blood. Recently, Aloe Vera has been used for different used range from cosmetic product and health care supplements. Aloe Vera 100% Gel 12 oz is gel which mainly ingredients with aloe. For adding information, this herbal is also popular with its benefits to healing any skin problems.
Furthermore, this 100% gel product delivers ability to deal with your skin problems such as pimples, red marks and scars. The advantages of Aloe in that gel are helping to increase the oxygen levels for the skin. The next product is Lily of the Desert – Aloe Vera Juice Whole Leaf, 32 floz which offers refreshing, soothing, nutritious juice drink to overcome antioxidants substance. Of course help you to deal with minor cuts, insect bites, skin irritations or a skin moisturizer. For daily basis, it is better to mix the juice with other fragrance. Aloe Vera is also scientifically proven to have antifungal benefits. It is not only helps in healing the acne but also to prevent your health. Beside aloe vera, there are also coconut water or tea tree oil as healthy products for us.
Hepatitis C – Fighting a Viral Infection Requires Medical Resources
For people dealing with hepatitis C, the long-term effects of the disease can be complicated. This disease comes after an
infection from a virus of the same name. The infection causes damage to the liver and it can reoccur for the rest of the person’s life. Initial infection treatment involves medications, ribavirin, and peginterferon. Almost half of all patients see a full cure after initial treatment. However, some patients will have chronic problems with the disease for the rest of their lives. For them, it is vital to have health insurance in place.
Hepatitis C causes damage to the liver and other areas of the body. In time, it can lead to cirrhosis and fibrosis. Fibrosis shows up as scarring in the liver. Cirrhosis is an advanced stage of scarring beyond fibrosis. Both lead to lower functioning of the liver. People who have the disease have a higher chance of developing liver cancer. In some cases, patients will require a liver transplant to survive. But, the virus will re-infect in most cases. Overall, medical treatments for this disease are for the long-term if initial treatment is not successful. And that translates into high medical costs. Without health insurance, patients often do not get the treatments they need.
If you have health insurance in place when you get a diagnosis with Hepatitis C, then you need to keep it at all costs. If you lose a job, you need to prioritize getting health insurance in place. That will make sure your disease has coverage. It is a good idea to consider switching to an individual health policy. These policies are yours and not tied to your employer. That means if you ever lose your job again your health care coverage doesn’t change. And you are not at the mercy of waiting periods for new employee health care coverage. Taking charge of your health means taking charge of your health care coverage as well.
Hepatitis C causes other medical conditions outside of the liver. Kidney inflammation is often present in some patients. Others experience vasculitis of the smaller blood vessels. It contributes to the development of diabetes. There are many other medical conditions directly associated with this disease. These conditions pop up at different times in different patients. That is another reason why it is important to get and maintain health care coverage with this chronic condition. It is a crucial piece in fighting this disease.
Dental Implants Consultation and Treatment Planning
Dental implants are artificial tooth replacements used to replace a missing tooth or teeth, helping to stop or prevent
jaw bone loss. The dental implant procedure is categorized as a form of prosthetic (artificial replacement) dentistry, though it also is a form of cosmetic dentistry.
By replacing missing tooth roots, implants offer more than an esthetic enhancement, providing people with the strength and durability required to eat all the foods they love, without struggling to chew. Although you have a number of restorative options for the treatment of missing teeth, none have proven to be as functionally effective and durable as implants.
In many cases, dental implants may be the only logical choice for the restoration of all necessary functionality of the teeth and supporting structures.
To determine if implants are right for you, a consultation with your dentist, oral surgeon, and/or periodontist or prosthodontist is needed. During this appointment, your dental professional will conduct a thorough examination of your teeth and gums. This may involve a combination of X-rays and computer tomography scans (CT scans) to ensure that sufficient bone structure exists for placing the implant(s), and to determine the exact location the implant should be placed.
Based on the condition of your oral tissues, oral hygiene and personal habits, and your commitment to follow your dentist’s aftercare instructions, your dentist will advise you of your most appropriate dental implant treatment plan. Some patients with insufficient bone or gum tissue require bone or soft tissue grafts, and/or the use of small diameter implants (also called mini implants).
Your treatment plan could involve the immediate placement of an implant and restoration at the same appointment, or require separate procedures to place the implant, allow healing and then place the restoration. In some instances, a series of procedures may be required to place tissue and bone grafting materials, allow time for healing, place the implant and allow it to integrate with your bone, and then place the restoration. Depending on your situation, your dental professional will advise you of how long the entire treatment process will take, how many appointments will be necessary and what you can expect after each procedure.
The consultation also will include discussion of options for local anesthesia (to numb the affected and surrounding areas) and sedation dentistry, if necessary.
Stem Cells and Cancer: A Multi-Edged Sword
The relationship between cancer and stem cells is turning out to be a fascinatingly complex one. Stem cells are now helping scientists identify the most fundamental precursors to cancer, and leading to much more selective pathways to target with drugs and other treatments. In fact, we seem to be on the verge of a whole new way of thinking about — and treating — deadly cancers.
Cancer is one of the leading causes of death throughout the industrialized world, running neck-and-neck with heart
disease as a cause of mortality. But with decades of research now invested, doctors still speak of cancer prognoses in terms of remissions, recurrence, or non-recurrence, never in the confident terminology of a “cure.” However, new findings in stem cell research are now causing scientists to rethink both the causes and possible outcomes of the disease.
It is well recognized that the essential problem in cancerous tumors is “cells gone wild” — cells that divide out of control, creating abnormal masses, colonizing and destroying normal tissues.
But very recently, scientists discovered that not all cancer cells are created equal. Within a hierarchy of cells within tumors, only a very small number of the cells are capable of initiating and spreading cancers. These cells, which also happen to be resistant to chemotherapy and radiation, have been called cancer stem cells. Cancer often recurs after tumor-shrinking treatment because even though millions of tumor cells may have been destroyed, the treatment leaves behind the cancer stem cells. So far, cancercausing stem cells have been identified in skin, breast, bone, brain, blood and liver cancers, and the thinking is that there may be a specific type of stem cell at the root of every type of cancer.
Although stem cells may be at the root of every cancer, it doesn’t follow that all stem cells cause cancer. Most stem cells, including embryonic, adult or gestational stem cells, give rise to
healthy cells and tissues. It is only a tiny percentage that set the stage for cancer, but as tests in animals show, it only takes a tiny number of cancer stem cells to set the disease in motion. One problem that makes this research difficult is the fact that cancerinitiating stem cells are not only rare, they are extremely hard to identify in cultures. Even so, several research teams throughout the world are now studying these cells closely to determine how they are both like and unlike normal stem cells — in other words, what causes a normal stem cell to go wrong? Especially interesting to cancer specialists are the protein signaling pathways — especially the signals of proteins dubbed Sonic Hedgehog, Gli-1, Gli-2 and Gli-3 — which are utilized by all types of stem cells. One theory is that something goes haywire in one or more of these pathways, which makes a good stem cell go bad.